You’ve probably heard it by now: your biological age matters more than the number of candles on your last birthday cake. Knowing how old your body really is isn’t just interesting: it’s powerful data you can use to improve your health. Three tests lead the space in 2026: TruAge vs GlycanAge vs TheDNACompany. In this guide, we compare them head-to-head so you can choose the best biological age test for your goals.
What do TruAge, GlycanAge, and TheDNACompany age tests actually measure?
TruAge uses blood-based DNA methylation to assess aging speed and organ health. GlycanAge analyzes immune and inflammation aging through IgG glycans. The DNA Company offers a saliva test with broader wellness markers like memory and vision.
TruAge (TruDiagnostic)
TruAge measures biological age using DNA methylation. Developed alongside top research institutions like Harvard, Yale, Duke, and Columbia, it leverages industry-leading algorithms: OMICmAge, DunedinPACE, and SYMPHONYAge.
These give insights not just into your biological age but also how fast you’re aging, organ-specific aging, and even telomere length.
- Sample type: Blood (finger-prick)
- Turnaround: 3–4 weeks
- Accuracy: Validated in multiple peer-reviewed studies; predictive accuracy around 98–99%
GlycanAge
GlycanAge approaches biological age differently, it measures glycans attached to immunoglobulin G (IgG), reflecting your immune health and inflammation levels. Glycans reveal how lifestyle and inflammation impact your aging process, making it sensitive to lifestyle shifts.
- Sample type: Blood (finger-prick)
- Turnaround: 3–5 weeks
- Accuracy: Validated by decades of glycoscience research, widely used in clinical studies (Harvard)
TheDNACompany
The DNA Company takes a broader functional genomics approach rather than focusing on a single aging clock. It combines genetic trait analysis with methylation-based biological age and telomere projections, then pairs the results with a one-on-one expert consultation. The goal is not just to show how old you are biologically, but to explain why and what to do about it across detox pathways, hormones, sleep, cognition, and metabolism.
- Sample type: Saliva (cheek swab)
- Turnaround: ~4–6 weeks
- Accuracy: Uses established genetic and methylation markers for biological age estimation; designed for personalized interpretation and actionable coaching rather than pure clock precision
Head-to-Head Comparison: TruAge vs GlycanAge vs The DNA Company
TruAge
Best Overall | 
The DNA Company
Coaching + Genetics | 
GlycanAge
Immune Focus | |
|---|---|---|---|
| Measurement Method | DNA methylation (blood) | Genetics + methylation + telomere projections (saliva) | IgG glycan profile (blood) |
| Accuracy & Validation | Peer-reviewed clocks (98–99%) | Action-focused interpretation with expert guidance | Clinically validated glycoscience |
| Turnaround Time | 3–4 weeks | ~4–6 weeks | 3–5 weeks |
| Extra Insights | Organ aging, pace of aging, telomeres | Detox, hormones, sleep, cognition + 1-on-1 coaching | Inflammation & immune balance |
| Price | $299 | Varies by program | ~$299 |
|
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🥇 TruAge
Best OverallMethod: DNA methylation (blood)
Why it stands out: Organ-level aging and pace tracking.
Price: $299
🧠 The DNA Company
Coaching + GeneticsMethod: Genetics + methylation + telomeres (saliva)
Why it stands out: Real interpretation with expert coaching.
🛡️ GlycanAge
Immune FocusMethod: IgG glycan profiling (blood)
Why it stands out: Tracks inflammation and immune aging.
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TruAge, GlycanAge, and TheDNACompany Discount Codes
🎁 Enjoy Exclusive Discounts for Our Readers
GlycanAge | 10% Off
The DNA Company | 10% Off
TruAge | 12% Off
Which biological age test is best for you?
Choose TruAge for detailed metrics, GlycanAge for immune tracking, or The DNA Company for a broad health overview.
- TruAge: If you’re a biohacker or longevity enthusiast looking for precise organ-level insights and comprehensive aging metrics, TruAge is your gold standard (Harvard on biological clocks).
- GlycanAge: Ideal if you’re particularly interested in inflammation, immune system aging, or hormonal impacts like menopause or stress.
- The DNA Company: Best if you want personalized guidance, not just numbers—combining genetics, methylation age, and telomere projections with 1-on-1 expert interpretation.
What can you do with your biological age results?
Use them to guide targeted lifestyle changes, whether it’s cardio for heart health, anti-inflammatory diets, or memory-boosting habits, based on what your test reveals.
One of the biggest mistakes people make is getting their biological age score and then doing nothing with it. Here’s exactly how you can apply these insights into everyday life:
TruAge: Precision Lifestyle Changes
TruAge delivers a detailed breakdown of how each organ system is aging. For example, if your cardiovascular system is flagged as aging faster than the rest of your body, you can prioritize targeted lifestyle shifts like cardio training, heart-healthy foods, and stress management. Harvard researchers confirm that lifestyle interventions can measurably reverse signs of biological aging (Harvard Study on Aging Reversal, 2023).
If your immune or inflammation scores are high, you might benefit from anti-inflammatory supplements such as omega-3 or curcumin, alongside better sleep and fasting protocols. The goal is simple: incremental improvements tailored exactly to your biology.
GlycanAge: Adjust Your Habits, Track Progress
GlycanAge focuses on inflammation and immune system aging. If your results reveal chronic stress is aging you faster, that’s a call to action. Science links stress to immune decline (NIH Study on Stress and Immune Aging, 2022). A smart response could be daily meditation, yoga, or time in nature.
GlycanAge is highly sensitive to lifestyle changes. Retest in 6 months and see whether your stress-management or dietary shifts lowered your biological immune age. This makes it ideal if you’re experimenting with new habits and want measurable proof they work.
The DNA Company: Genetics With Real Guidance
The DNA Company goes beyond a single aging score by combining genetic trait analysis, methylation-based biological age, and telomere projections. Instead of raw data, you get clear explanations of how your genes affect detox, hormones, sleep, and cognition.
What makes it different is the one-on-one expert consultation. Your results are reviewed with a specialist who helps translate complex genetics into practical lifestyle and nutrition decisions. This makes it ideal if you want context, coaching, and direction, not just numbers.
Why Choosing the Right Epigenetic Test Matters
Consider two scenarios that show clearly how picking the right test can drastically change your outcome:
Scenario A: John (age 45, fitness-focused)
John chose TruAge because he’s been optimizing fitness and health. His TruAge test showed his biological age as slightly younger, but his cardiovascular age lagged behind due to genetic predispositions. This data prompted John to fine-tune his fitness regime, incorporating more cardio-intensive workouts and nutritional tweaks focused on heart health. After a year, his follow-up showed marked improvements in his cardiovascular scores, proving the targeted approach genuinely worked.
Scenario B: Sarah (age 53, high-stress job)
Sarah opted for GlycanAge, suspecting stress was prematurely aging her. Sure enough, her biological age came back significantly older, flagged by elevated inflammatory markers. Sarah used these results as motivation to adjust her lifestyle radically. She started daily mindfulness sessions and introduced anti-inflammatory foods like turmeric and olive oil. Retesting nine months later, her GlycanAge scores dropped by 5 years biologically, a tangible result directly connected to her actionable lifestyle changes.
These real-life cases underline why your choice between TruAge, GlycanAge, and The DNA Company matters. Your biological age isn’t just a number, it’s a roadmap for real, meaningful change.
Created by SimplyAntiAging.com’s Editorial Research Team
Reviewed and updated for accuracy in December 2025.
