Nucleus Genomics is one of the few companies offering both genetic and epigenetic testing in a single platform. That means you get insight into your DNA — ancestry, traits, health risks — and your current biological age.
In this Nucleus Genomics age test review, we break down how it works, what you get, and how it compares to other leading biological age kits in 2025.
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Table of Contents
What does the Nucleus Genomics age test measure?
The Nucleos Genomics age test analyzes both your DNA (genetics) and your current biological age (epigenetics), giving you insights into ancestry, traits, health risks, and how fast your body is aging.
You collect both samples at home and mail them back. This dual method gives you a complete view: your long-term genetic blueprint and how your current lifestyle is shaping how you age.
It measures:
- Biological age via DNA methylation
- Epigenetic risk scores (early versions)
- Ancestry breakdown
- Trait insights (like caffeine sensitivity, endurance, etc.)
- Carrier status and genetic predispositions
What do you get in the Nucleus Genomics report?
You get access to a digital dashboard with your biological age, ancestry, lifestyle traits, genetic risks, and educational recommendations.
- Biological age vs chronological age
- Lifestyle-linked aging insights
- Detailed ancestry composition
- Traits like sleep, muscle strength, or alcohol tolerance
- Disease risk estimates based on your genetics (e.g., cardiovascular, metabolic)
- Actionable recommendations and educational guides
How accurate is the Nucleus Genomics age test?
Nucleus uses peer-reviewed DNA methylation methods for age estimation, although they don’t specify which aging clock they use (e.g., Horvath or DunedinPACE). Their internal platform was developed with partnerships from:
While it’s not as detailed as TruAge or NOVOS in terms of biological age breakdown, it offers strong overall age estimation and a broader genomic context.
The test’s genetic analysis follows standard Illumina genotyping used in academic research.
Why do biohackers choose Nucleus Genomics?
Because it combines DNA traits and biological age in one test, offering a full-body view for prevention, optimization, and self-tracking. It is perfect for those who:
- Want both ancestry + biological age in one kit
- Are curious about how genetics and epigenetics interact
- Prefer detailed trait analysis (sleep, fitness, etc.) alongside aging
- Are looking for early prevention based on your DNA profile
- Like educational tools and scientific transparency
How can you use your Nucleus age test results to improve aging?
Use your biological age score and trait data to adjust sleep, diet, or exercise — and discuss genetic risks with a coach or practitioner if needed.
- Order your kit and collect two samples (saliva and blood spot)
- Receive your full genomic and epigenetic report online
- Review your biological age, traits, and risks
- Follow up with lifestyle changes or deeper testing if needed
- Retest epigenetics in the future if using the longevity dashboard (still limited)
- Download raw data if you want to explore it with your doctor or through third-party tools.
How does Nucleus compare to other epigenetic tests?
🧬 Nucleus vs TruAge
TruAge is clinical-grade and goes deeper into organ aging and methylation pace. Nucleus adds genomics and traits but is lighter on epigenetic detail.
🧠 Nucleus vs Elysium Index
Elysium tracks aging across 9 systems using saliva. Nucleus gives one biological age score but adds full DNA trait mapping and disease risk data.
💡 Nucleus vs NOVOS Age
NOVOS measures aging pace and telomeres with blood. Nucleus gives less lifestyle feedback but adds ancestry + genetic risk info.
🧪 Nucleus vs Tally
Tally is built for lifestyle tracking using a cheek swab. Nucleus is broader and more educational, but not ideal for monthly habit tracking.
How much does Nucleus cost and where is it available?
💵 One-time price: $349
🧬 Includes both DNA + biological age testing
📲 Mobile app: Not yet available
📦 HSA/FSA eligible: ❌ No
🌍 Available in: US, Canada, UK, EU, and select countries
Biological age retesting isn’t currently offered on a subscription basis, it’s a one-time snapshot.
What are users saying about Nucleus age test?
🧠 On Reddit:
- “Best option if you want one test for everything.”
- “Ancestry + age in one dashboard is great.”
- “Not ideal for retesting aging monthly, but packed with data.”
💬 On Quora:
- Often recommended for people new to genetics and epigenetics
- Liked for its scientific credibility and partnerships
- Users enjoy the clear ancestry and trait insights, especially compared to 23andMe
FAQs
Does Nucleus Genomics use the Horvath Clock or DunedinPACE for biological age?
No, Nucleus doesn’t specify which epigenetic clock it uses. Unlike TruAge or NOVOS, which clearly state their use of DunedinPACE or Horvath-based models, Nucleus uses its own proprietary algorithm. That means the biological age score is useful but not directly comparable to academic research tools.
Can I upload my 23andMe or AncestryDNA data to Nucleus?
Not at this time. Nucleus Genomics requires you to submit a new sample for their system. Their platform does not currently support raw data uploads from other DNA services like 23andMe or AncestryDNA.
Does Nucleus Genomics offer health reports based on polygenic risk scores (PRS)?
Yes, but only for select conditions. Nucleus uses PRS to estimate risk for diseases like type 2 diabetes or heart conditions. These are based on large-scale genomic studies, but not intended as medical diagnoses. The reports are educational and best used in consultation with a professional.
Is Nucleus Genomics HIPAA-compliant?
While they claim to follow strict data protection and encryption protocols, they are not officially HIPAA-certified. Your data is stored securely, and users can request deletion at any time — but it’s worth confirming this if privacy is a top concern for you.
Can children or teenagers use the Nucleus test?
No, currently Nucleus Genomics is only available to individuals aged 18 and older. Since the test includes genetic risk reports and lifestyle traits, it’s intended for adults making health and longevity decisions.
Does Nucleus Genomics plan to offer ongoing biological age tracking in the future?
They haven’t launched that yet, but the company has mentioned upcoming longevity features. Currently, the biological age test is a one-time snapshot. Ongoing tracking, if released, could make it more competitive with brands like TruAge or GlycanAge.
Can this test tell me what supplements to take for healthy aging?
Not directly. Nucleus Genomics does not offer supplement recommendations or personalized plans. However, based on your trait results and aging score, you can work with a health coach or longevity practitioner to build a strategy. Some users use the DNA results to guide decisions about vitamin D, omega-3s, or anti-inflammatory routines.
Written by the editorial team at Simply Anti-Aging.
Reviewed for accuracy and updated in July 2025.
