This biological age test kit comparison reviews the best at-home kits of 2025 by accuracy, method, and health insights. These tests show how fast your body is aging at the cellular level using DNA methylation, glycan profiling, or genome sequencing.
Your biological age is different from your birthday age. It reflects how lifestyle, stress, and genetics shape your health. Knowing it helps you see if your habits are keeping you younger or pushing you to age faster.
In this guide, we compare leading kits like TruAge, GlycanAge, TheDNACompany, EasyDNA, and NOVOS Age, so you can choose the most accurate and affordable option in 2025.
Key Takeaways
- Biological age estimates how “old” your body acts: it can be younger or older than your birthday age.
- Blood-based DNA methylation tests are the most consistent if you plan to re-test and track changes over time.
- Different methods measure different things: some focus on overall risk, some on how fast you’re aging right now, and some on immune or inflammation changes.
- Telomeres are interesting but less reliable on their own for personal tracking compared with methylation or immune-glycan signals.
- The three main contenders in 2025 are TruAge, GlycanAge, and NOVOS.
Jump to a Section
Which Biological Age Test Kits are Best in 2025?
🥇 TruAge, GlycanAge, and NOVOS lead in accuracy and trust.
Each offers unique methods, from DNA methylation to immune tracking.
- 🧬 Measures 950,000+ methylation DNA markers
- ⏱️ Tracks your aging speed organ by organ
- 📊 Built for deep, science-backed insights
- 🧪 Measures biological age via DunedinPACE + Telomeres
- 🩸 Sample: Blood
- 📘 55-page report + longevity app
- 📱 App for progress tracking
- 💳 HSA/FSA eligible
- 🧫 Measures immune age through glycan science
- 🔄 Detects fast changes from stress or sleep
- 🧘♀️ Helps track recovery, aging, and health
Some links may be affiliate. We may receive a small fee if you purchase at no extra cost for you.
What do biological age tests actually measure?
They measure aging biomarkers like DNA methylation, inflammation, or telomeres.
Each brand focuses on different markers depending on the test method.
- Epigenetic Age Tests: These use DNA methylation patterns (chemical changes to your DNA) to estimate your biological age.
- Health Insight Kits: Some go further by including glycan profiling, genetic trait analysis, or even organ-specific aging scores.
Some premium tests also report your pace of aging, telomere length, or organ-level data, giving you a fuller picture of how your body is aging and responding to your lifestyle.
How do epigenetic clocks actually calculate your real age?
They analyze changes in DNA methylation patterns linked to aging. These clocks are based on large datasets and peer-reviewed science.
The most respected tests are built on DNA methylation models published in journals like Nature Aging or developed by major universities.
- Horvath Clock (2013), GrimAge (2019), and DunedinPACE (2021) are strongly linked to disease risk, mortality, and physical decline.
- A 2023 study showed that caloric restriction and targeted exercise can reverse biological age, especially when measured with DunedinPACE.
- GlycanAge is based on over 30 years of glycoscience research and reflects immune system aging, which is responsive to stress, sleep, and inflammation.
- Telomere length, while still included in some kits, is no longer considered a reliable standalone aging marker due to wide natural variability.
Top labs like Harvard, Yale, Duke, and Columbia continue to use these tools in published studies on PTSD, ketamine, metabolic disease, and even longevity supplements.
Best Biological Age Test Kit Comparison Table
| Test Kit | Price | Method | Sample | Features | App/Coach | HSA/FSA | Accuracy |
|---|---|---|---|---|---|---|---|
TruAge ⭐ | $249 | OMICmAge, SYMPHONYAge, DunedinPACE | Blood | Organ age, telomeres, pace of aging | Dashboard | ✅ Yes | ★★★★★
Order |
GlycanAge | ~$299 | IgG Glycan profiling | Blood | Immune age, inflammation tracking | 1:1 Consult | ❌ No | ★★★★☆
Order |
| $499 + $39/yr | Whole Genome Sequencing | Cheek swab | Full disease & trait breakdown | Dashboard | ✅ Yes | ★★★★★
Order | |
| $399 | DNA Traits + DunedinPACE | Blood + Saliva | Coaching + trait testing | ✅ Coach | ❌ No | ★★★★☆
Order | |
 EasyDNA | $129 | DNA methylation | Saliva | Score + basic recommendations | PDF Only | ❌ No | ★★★★☆
Order |
| $273 | Methylation + DNA Bundle | Saliva | Inflammation, hearing, vision age | ✅ App | ❌ No | ★★★★☆
Order | |
NOVOS Age | $349 | DunedinPACE + Telomeres | Blood | 55-page report + longevity app | ✅ App | ✅ Yes | ★★★★☆
Order |
| $299 | Methylation (APEX chip) | Saliva | 9 body systems + aging speed | Web Only | ❌ No | ★★★★☆
Order | |
| $299 | Horvath Clock + 2K CpGs | Blood or Urine | Uses SWARM sequencing method | Web Only | ❌ No | ★★★★☆
Order | |
| $249 | Cheek methylation (CheekAge) | Cheek swab | Lifestyle tracking + dashboard | Web Only | ❌ No | ★★★☆☆
Order |
TruAge ⭐
GlycanAge
Nucleus Genomics
The DNA Company
EasyDNA
MyToolbox Genomics
NOVOS Age
Elysium Index
myDNAge
TallyAge
Biological Age Test Discount Codes
🎁 Exclusive Reader Discounts
Our Rating Methodology
- Accuracy weighting (40%): peer-reviewed clocks, CpG sites analyzed, sample type (blood vs saliva/cheek).
- Clinical relevance (20%): pace-of-aging metrics, organ/immune signals, repeatability for retesting.
- User experience (15%): dashboard/app quality, coaching, turnaround time.
- Transparency (15%): published methods, labs, references.
- Value (10%): price, HSA/FSA, discounts.
Rankings reflect the criteria above and are independent of affiliate relationships.
Best Biological Age Tests to Track Lifestyle Changes Over Time
If you’re serious about biohacking, choose a test that tracks how your habits, like fasting, sleep, or supplements, actually change your biological age.
🧬 TruAge: Tracks aging pace, telomeres, and 11 organs. Ideal for long-term monitoring and comparing interventions.
🔥 GlycanAge: Great for inflammation and immune aging insights. Especially responsive to stress, menopause, and lifestyle tweaks.
🏃♂️ TallyAge: Built for retesting every 6 months. Sensitive to fitness, alcohol, diet, and other daily habits.
📱 NOVOS Age: Combines epigenetic testing with an AI longevity app that guides habit change and supplement use.
Epigenetic Age Tests With Coaching, Dashboards & In-App Insights
🧑⚕️ The DNA Company: Comes with a 1-on-1 coaching session to help you interpret your results and build a personalized action plan.
📱 My Toolbox Genomics: Easy-to-use app with scores for inflammation, memory, and hearing age. Great for tracking trends.
📚 NOVOS: Includes access to 100+ mini reports on gut health, vitamins, pollution, and more. Ideal for general wellness tracking.
Which Biological Age Test Is the Most Accurate?
If you care about getting precise results, your best bet is a blood-based DNA methylation test using a high number of CpG markers.
TruAge is the most advanced, it checks over 950,000 markers and uses 3 aging algorithms.
NOVOS Age checks over 850,000 markers and also gives you a telomere estimate.
Elysium Index is saliva-based but uses a special chip developed with Yale.
💡 Blood samples are more accurate, especially if you’re testing again later to track changes. Saliva and cheek swabs are easier, but less precise.
How to Take a Biological Age Test at Home
Order your test kit
Pick a kit in our comparison table
Register your kit
When it arrives, register it on the brand’s website or app using the unique code inside the box.
Collect your sample
Follow the instructions to give a blood drop, saliva tube, or cheek swab. Use the tools provided.
Send your sample to the lab
Seal your sample in the prepaid envelope or box and ship it back to the lab.
Get your results online
Within 2–5 weeks, log into your dashboard, app, or download a PDF report showing your biological age and lifestyle insights.
FAQ – Biological Age Test Kits & Epigenetic Clock Test Kits
What’s the difference between an epigenetic clock and a biological age test kit?
A biological age test shows how your body is aging, not just your birthday. An epigenetic clock test is one type of biological test that uses DNA methylation models, such as Horvath’s Clock or DunedinPACE, to estimate your actual cellular age.
Can I trust an at-home biological age test kit to be accurate?
Are biological age saliva tests as accurate as blood-based tests?
No. Blood-based kits provide a wider and more reliable picture of DNA methylation changes. Saliva tests are suitable for basic tracking, but not ideal for measuring intervention results like fasting or supplement effects.
Which test is best for tracking brain or cognitive aging?
Can a biological age test help me reduce my age?
How often should I retake a biological age or epigenetic test?
Most people retest every 3 to 12 months. This timing allows for measurable changes from lifestyle interventions such as cold therapy, circadian rhythm optimization, or dietary shifts.
What makes a DNA methylation test high quality?
The best DNA methylation tests analyze 850,000 or more CpG sites and use validated epigenetic clocks. Lower-quality kits often don’t publish how many sites they use, which limits their precision for biohackers.
Which biological age tests ship internationally?
What’s the best biological age test kit for biohackers?
If you want to validate your stack or track subtle changes, go with a high-resolution methylation test. Best options are TruAge for organ-specific aging and pace tracking, GlycanAge for stress and inflammation responsiveness and NOVOS Age for app-guided interventions. These are ideal for testing protocols, supplements, or routines.
Can I use HSA or FSA to pay for a biological age test?
Yes, but only some kits qualify. TruAge, NOVOS Age, The DNA Company, and Nucleus Genomics are usually HSA/FSA eligible in the U.S. Most others are not. Check with your provider before buying.
How long does it take to get results from a biological age test?
Turnaround varies. Some saliva-based kits deliver results in 1–2 weeks, while epigenetic tests using blood may take 3–5 weeks or longer. Plan accordingly if you’re testing before or after a health intervention.
References
- DNA methylation age of human tissues and cell types – Horvath
- DNA methylation age of human tissues and cell types – Genome Biology (Open Access)
- DNA methylation GrimAge strongly predicts lifespan and healthspan – Lu et al.
- Effect of long-term caloric restriction on DNA methylation measures of biological aging (CALERIE/DunedinPACE) – Nature Aging
- Cutting calories may slow the pace of aging in healthy adults – NIA News
- Effects of estradiol on biological age measured using the glycan clock – Jurić et al.
- Effects of estradiol on biological age (Open Access) – PMC
- Immunoglobulin G glycome in transition from pre- to post-menopause – Deriš et al.
- Telomere Length as a Marker of Biological Age – Review
- Techniques for assessing telomere length – Review
📚 How to Cite This Page
title={Best Biological Age Test Kits 2025: Evidence-Based Comparison},
author={Robert, J.},
year={2025},
url={https://simplyantiaging.com/biological-age-test-kit-comparison/}
}
Reviewed by Dr. Robert | Longevity Expert & Researcher
Written by the editorial team at Simply Anti-Aging.
Reviewed for accuracy and updated in October 2025.
