This biological age test kit comparison ranks the best at-home biological and epigenetic tests of 2025 by method, accuracy, and key health insights for biohacking and optimization.
Your biological age reflects how fast your body is aging at the cellular level. It’s shaped by your lifestyle, environment, stress, and genetics, and it may be older or younger than your actual age.
In 2025, more people than ever are using biological age test kits at home. These tools are based on real science: DNA methylation, glycan profiling, and in some cases, whole genome sequencing. They can reveal your aging speed, immune system health, and even organ-specific aging.
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🥇 Which Biological Age Test Kits are Best in 2025?
TruAge, GlycanAge, and EasyDNA lead in accuracy and trust.
Each offers unique methods, from DNA methylation to immune tracking.
TruAge
🥇 Best Overall Accuracy
🧬 Measures 950,000+ methylation DNA markers
⏱️ Tracks your aging speed organ by organ
📊 Built for deep, science-backed insights
🎁 12% Discount Code
TRUINSIDER12
GlycanAge
🛡️ Best for Immune Health
🧫 Measures immune age through glycan science
🔄 Detects fast changes from stress or sleep
🧘♀️ Helps track recovery, aging, and health
🎁 10% Discount Code
DAILYBIOHACKING
EasyDNA
💰 Best Budget Option
🧪 Saliva test with real epigenetic results.
⚡ Clear PDF report with fast turnaround
👍 Ideal intro kit for tracking bio age on a budget
🎉 The Cheapest Age Test
EasyDNA
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What do biological age tests actually measure?
They measure aging biomarkers like DNA methylation, inflammation, or telomeres.
Each brand focuses on different markers depending on the test method.
- Epigenetic Age Tests: These use DNA methylation patterns (chemical changes to your DNA) to estimate your biological age.
- Health Insight Kits: Some go further by including glycan profiling, genetic trait analysis, or even organ-specific aging scores.
Some premium tests also report your pace of aging, telomere length, or organ-level data, giving you a fuller picture of how your body is aging and responding to your lifestyle.
How do epigenetic clocks actually calculate your real age?
They analyze changes in DNA methylation patterns linked to aging. These clocks are based on large datasets and peer-reviewed science.
The most respected tests are built on DNA methylation models published in journals like Nature Aging or developed by major universities.
- Horvath Clock (2013), GrimAge (2019), and DunedinPACE (2021) are strongly linked to disease risk, mortality, and physical decline.
- A 2023 study showed that caloric restriction and targeted exercise can reverse biological age, especially when measured with DunedinPACE.
- GlycanAge is based on over 30 years of glycoscience research and reflects immune system aging, which is responsive to stress, sleep, and inflammation.
- Telomere length, while still included in some kits, is no longer considered a reliable standalone aging marker due to wide natural variability.
Top labs like Harvard, Yale, Duke, and Columbia continue to use these tools in published studies on PTSD, ketamine, metabolic disease, and even longevity supplements.
Best Biological Age Test Kit Comparison Table
| Test Kit | Price | Method | Sample | Features | App/Coach | HSA/FSA | Accuracy |
|---|---|---|---|---|---|---|---|
TruAge ⭐ | $499 | OMICmAge, SYMPHONYAge, DunedinPACE | Blood | Organ age, telomeres, pace of aging | Dashboard | ✅ Yes | ★★★★★ |
| $275 | ML methylation + traits | Saliva | Eye, memory, inflammation, fitness | ✅ App | ❌ No | ★★★★☆ | |
GlycanAge | ~$299 | IgG Glycan profiling | Blood | Immune age, inflammation tracking | 1:1 Consult | ❌ No | ★★★★☆ |
| $499 + $39/yr | Whole Genome Sequencing | Cheek swab | Full disease & trait breakdown | Dashboard | ✅ Yes | ★★★★★ | |
| $399 | DNA Traits + DunedinPACE | Blood + Saliva | Coaching + trait testing | ✅ Coach | ❌ No | ★★★★☆ | |
EasyDNA | $129 | DNA methylation | Saliva | Score + basic recommendations | PDF Only | ❌ No | ★★★★☆ |
| $273 | Methylation + DNA Bundle | Saliva | Inflammation, hearing, vision age | ✅ App | ❌ No | ★★★★☆ | |
| $349 | DunedinPACE + Telomeres | Blood | 55-page report + longevity app | ✅ App | ✅ Yes | ★★★★☆ | |
| $299 | Methylation (APEX chip) | Saliva | 9 body systems + aging speed | Web Only | ❌ No | ★★★★☆ | |
| $299 | Horvath Clock + 2K CpGs | Blood or Urine | Uses SWARM sequencing method | Web Only | ❌ No | ★★★★☆ | |
| $249 | Cheek methylation (CheekAge) | Cheek swab | Lifestyle tracking + dashboard | Web Only | ❌ No | ★★★☆☆ |
TruAge ⭐ 
DoNotAge GlycanAge 
Nucleus Genomics 
The DNA Company EasyDNA 
MyToolbox Genomics 
NOVOS Age 
Elysium Index 
myDNAge 
TallyAge Biological Age Test Discount Codes
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Best Biological Age Tests to Track Lifestyle Changes Over Time
If you’re serious about biohacking, choose a test that tracks how your habits, like fasting, sleep, or supplements, actually change your biological age.
- 🧬 TruAge: Tracks aging pace, telomeres, and 11 organs. Ideal for long-term monitoring and comparing interventions.
- 🔥 GlycanAge: Great for inflammation and immune aging insights. Especially responsive to stress, menopause, and lifestyle tweaks.
- 🏃♂️ TallyAge: Built for retesting every 6 months. Sensitive to fitness, alcohol, diet, and other daily habits.
- 📱 NOVOS Age: Combines epigenetic testing with an AI longevity app that guides habit change and supplement use.
Epigenetic Age Tests With Coaching, Dashboards & In-App Insights
🧑⚕️ The DNA Company: Comes with a 1-on-1 coaching session to help you interpret your results and build a personalized action plan.
📱 My Toolbox Genomics: Easy-to-use app with scores for inflammation, memory, and hearing age. Great for tracking trends.
📚 DoNotAge: Includes access to 100+ mini reports on gut health, vitamins, pollution, and more. Ideal for general wellness tracking.
Which Biological Age Test Is the Most Accurate?
If you care about getting precise results, your best bet is a blood-based DNA methylation test using a high number of CpG markers.
TruAge is the most advanced, it checks over 950,000 markers and uses 3 aging algorithms.
NOVOS Age checks over 850,000 markers and also gives you a telomere estimate.
Elysium Index is saliva-based but uses a special chip developed with Yale.
💡 Blood samples are more accurate, especially if you’re testing again later to track changes. Saliva and cheek swabs are easier, but less precise.
FAQ – Biological Age Test Kits & Epigenetic Clock Test Kits
What’s the difference between an epigenetic clock and a biological age test kit?
A biological age test shows how your body is aging, not just your birthday. An epigenetic clock test is one type of biological test that uses DNA methylation models, such as Horvath’s Clock or DunedinPACE, to estimate your actual cellular age.
Can I trust an at-home biological age test kit to be accurate?
Are biological age saliva tests as accurate as blood-based tests?
No. Blood-based kits provide a wider and more reliable picture of DNA methylation changes. Saliva tests are suitable for basic tracking, but not ideal for measuring intervention results like fasting or supplement effects.
Which test is best for tracking brain or cognitive aging?
Can a biological age test help me reduce my age?
How often should I retake a biological age or epigenetic test?
Most people retest every 3 to 12 months. This timing allows for measurable changes from lifestyle interventions such as cold therapy, circadian rhythm optimization, or dietary shifts.
What makes a DNA methylation test high quality?
The best DNA methylation tests analyze 850,000 or more CpG sites and use validated epigenetic clocks. Lower-quality kits often don’t publish how many sites they use, which limits their precision for biohackers.
Which biological age tests ship internationally?
What’s the best biological age test kit for biohackers?
If you want to validate your stack or track subtle changes, go with a high-resolution methylation test. Best options are TruAge for organ-specific aging and pace tracking, GlycanAge for stress and inflammation responsiveness and NOVOS Age for app-guided interventions. These are ideal for testing protocols, supplements, or routines.
Can I use HSA or FSA to pay for a biological age test?
Yes, but only some kits qualify. TruAge, NOVOS Age, The DNA Company, and Nucleus Genomics are usually HSA/FSA eligible in the U.S. Most others are not. Check with your provider before buying.
How long does it take to get results from a biological age test?
Turnaround varies. Some saliva-based kits deliver results in 1–2 weeks, while epigenetic tests using blood may take 3–5 weeks or longer. Plan accordingly if you’re testing before or after a health intervention.
Written by the editorial team at Simply Anti-Aging.
Reviewed for accuracy and updated in July 2025.
